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QuantiGene Plex Assay

QuantiGene Plex - Complete Bibliography (Updated 05-05-0214) PDF

QuantiGene Plex - Bibliography 2011-2014 (Updated 05-05-2014) PDF


Cecchini M. J., et al. A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene targeted mice. Mol Cell Biol (2014).

Fu Z. D. and Klaassen C. D. Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice. Toxicol Appl Pharmacol 274(1):137-46 (2014).

Krishnan S., et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis 209(6):931-9 (2014).

Li W., et al. Noninvasive Imaging of In Vivo MuRF1 Expression during Muscle Atrophy. PLoS ONE 9(4):e94032 (2014).

MacArthur J. W., et al. Preclinical Evaluation of the Engineered Stem Cell Chemokine Stromal Cell–Derived Factor 1α Analog in a Translational Ovine Myocardial Infarction Model. Circul. Res. 114(4):650-59 (2014).

Osinusi A., et al. Comparative efficacy, pharmacokinetic, pharmacodynamic activity, and interferon stimulated gene expression of different interferon formulations in HIV/HCV genotype-1 infected patients. J Med Virol 86(2):177-85 (2014).

Rai M. F., et al. Relationship of gene expression in the injured human meniscus to body mass index: A biological connection between obesity and osteoarthritis. Arthritis Rheumatol (2014).

Ripamonti C., et al. Clearance of Pneumocystis murina infection is not dependent on MyD88. Microbes Infect (2014).

Smith I. J., et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. Faseb J (2014).

Wood C. E., et al. Comparative time course profiles of phthalate stereoisomers in mice. Toxicol Sci 139(1):21-34 (2014).

Zhang Q., Lei X. and Lu H. Alterations of Epigenetic Signatures in Hepatocyte Nuclear Factor 4α Deficient Mouse Liver Determined by Improved ChIP-qPCR and (h)MeDIP-qPCR Assays. PLoS ONE 9(1):e84925 (2014).


Aminzadeh M. A., et al. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease. Xenobiotica (2013).

Armstrong L. E., et al. Effects of developmental deltamethrin exposure on white adipose tissue gene expression. J Biochem Mol Toxicol 27(2):165-71 (2013).

Armstrong T. A., et al. Quantification of transgene-derived double-stranded RNA in plants using the QuantiGene nucleic acid detection platform. J Agric Food Chem 61(51):12557-64 (2013).

Beh J. E., et al. SDF7, a group of Scoparia dulcis Linn. derived flavonoid compounds, stimulates glucose uptake and regulates adipocytokines in 3T3-F442a adipocytes. J Ethnopharmacol (2013).

Bodeman C. E., et al. Differential regulation of hepatic organic cation transporter 1, organic anion-transporting polypeptide 1a4, bile-salt export pump, and multidrug resistance-associated protein 2 transporter expression in lymphocyte-deficient mice associates with interleukin-6 production. J Pharmacol Exp Ther 347(1):136-44 (2013).

Cho H., et al. Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Nat Med 19(4):458-64 (2013).

Fathilah S. N., et al. Labisia pumila regulates bone-related genes expressions in postmenopausal osteoporosis model. BMC Complement Altern Med 13(1):217 (2013).

Fu Z. D. and Klaassen C. D. Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice. Toxicol Appl Pharmacol 273(3):680-90 (2013).

Gardai S. J., et al. Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease. PLoS ONE 8(8):e71634 (2013).

Gat-Viks I., et al. Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli. Nat Biotechnol 31(4):342-9 (2013).

Harding T. C., et al. Blockade of Nonhormonal Fibroblast Growth Factors by FP-1039 Inhibits Growth of Multiple Types of Cancer. Sci Transl Med 5(178):178ra39 (2013).

Haynes B. C., et al. Mapping functional transcription factor networks from gene expression data. Genome Res 23(8):1319-28 (2013).

Hays A., Apte U. and Hagenbuch B. Organic Anion Transporting Polypeptides Expressed in Pancreatic Cancer May Serve As Potential Diagnostic Markers and Therapeutic Targets for Early Stage Adenocarcinomas. Pharm Res (2013).

Hemmati F., et al. Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: Comparison with Memantine. Behav Brain Res (2013).

Hsu S., et al. CRT-124 Comparative In Vitro Effects Of Paclitaxel, Everolimus, And Tacrolimus On Macrophage-derived Foam Cells, Smooth Muscle Cells, And Endothelial Cells. JACC: Cardiovascular Interventions 6(2_S):S40-S (2013).

Hu X. Y., et al. Copy number variation at 6q13 is associated with lung cancer risk in a Han Chinese population. Exp Lung Res 39(10):427-33 (2013).

Jiang H., et al. Correlation between microtubule-associated gene expression and chemosensitivity of patients with stage II non-small cell lung cancer. Exp Ther Med 5(5):1506-10 (2013).

Lahteinen T., et al. Effect of Lactobacillus brevis ATCC 8287 as a feeding supplement on the performance and immune function of piglets. Vet Immunol Immunopathol (2013).

Lombardelli L., et al. HLA-G5 Induces IL-4 Secretion Critical for Successful Pregnancy through Differential Expression of ILT2 Receptor on Decidual CD4+ T Cells and Macrophages. J. Immunol. (2013).

MAN M., et al. Detection of the differential expression of interleukin gene in two rabbit strains with liquid suspension array system Chinese Journal of Comparative Medicine 23(2):R33 (2013).

Metzger D. C., et al. Development of a multiplex gene expression assay for components of the endocrine growth axis in coho salmon. Gen Comp Endocrinol 189(134-40 (2013).

More V. R., et al. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver. Drug Metab Dispos (2013).

More V. R., et al. Keap1 knockdown increases markers of metabolic syndrome after long-term fat diet feeding. Free Radic Biol Med (2013).

Nagalla S., et al. Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis. Genome Biol 14(4):R34 (2013).

Nickisch K., et al. Synthesis and antiprogestational properties of novel 17-fluorinated steroids. Steroids 78(9):909-19 (2013).

Nur Azlina M. F., et al. Tocotrienol Attenuates Stress-Induced Gastric Lesions via Activation of Prostaglandin and Upregulation of COX-1 mRNA. Evid Based Complement Alternat Med 2013:804796 (2013).

Orr M. T., et al. MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant. Eur. J. Immunol. (2013).

Pak-Wittel M. A., et al. Interferon-gamma mediates chemokine-dependent recruitment of natural killer cells during viral infection. PNAS 110(1):E50-9 (2013).

Potts M. B., et al. Using functional signature ontology (FUSION) to identify mechanisms of action for natural products. Sci Signal 6(297):ra90 (2013).

Qian X., et al. Inhibition of WISE Preserves Renal Allograft Function. J Am Soc Nephrol 24(1):66-76 (2013).

Rai M. F., et al. Transcriptome Analysis of Injured Human Meniscus Reveals a Distinct Phenotype of Meniscus Degeneration With Aging. Arthritis Rheum. 65(8):2090-101 (2013).

Reisman S. A., et al. Topical application of the synthetic triterpenoid RTA 408 activates Nrf2 and induces cytoprotective genes in rat skin. Arch Dermatol Res (2013).

Ruchi F., et al. A Multiplex High Content High Throughput Screening Platform Using iPS Cells Derived RPE. Invest. Ophthalmol. Vis. Sci. 54(6):2230 (2013).

van Heumen B. W., et al. Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls. Orphanet J Rare Dis 8(181 (2013).

van Heumen B. W., et al. Ursodeoxycholic acid counteracts celecoxib in reduction of duodenal polyps in patients with familial adenomatous polyposis: a multicentre, randomized controlled trial. Orphanet J Rare Dis 8:118 (2013).

van Kessel J. C., et al. Individual and Combined Roles of the Master Regulators AphA and LuxR in Control of the Vibrio harveyi Quorum-Sensing Regulon. J Bacteriol 195(3):436-43 (2013).

Walter R. B., et al. Significance of expression of ITGA5 and its splice variants in acute myeloid leukemia: A report from the children's oncology group. Am J Hematol (2013).

Wuttge D., et al. Increased serum type I interferon activity in early systemic sclerosis patients is associated with antibodies against Sjogren's syndrome antigens and nuclear ribonucleoprotein antigens. Scand J Rheumatol (2013).

Xue M., et al. Effects of reticuloendotheliosis virus infection on cytokine production in SPF chickens. PLoS ONE 8(12):e83918 (2013).

Yalcin E. B., et al. Down-regulation of sulfotransferase expression and activity in diseased human livers. Drug Metab Dispos (2013).

Zhan J., et al. Novel Anti-c-Mpl Monoclonal Antibodies Identified Multiple Differentially Glycosylated Human c-Mpl Proteins in Megakaryocytic Cells But Not in Human Solid Tumors. Monoclon Antib Immunodiagn Immunother 32(3):149-61 (2013).


Aleksunes L. M. and Klaassen C. D. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice. Drug Metab Dispos (2012).

Aleksunes L. M., et al. Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy. Toxicol Sci (2012).

Bengtsson A. A., et al. Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in patients with systemic lupus erythematosus.> Arthritis Rheum 64(5):1579-88 (2012).

Choi N. W., et al. Multiplexed detection of mRNA using porosity-tuned hydrogel microparticles. Anal Chem Oct 15 (2012).

Cui J. Y, Renaud H. J and Klaassen C. D. Ontogeny of novel cytochrome P450 gene isoforms during postnatal liver maturation in mice. Drug Metab Dispos (2012).

Fu Z. D, Csanaky I. L. and Klaassen C. D. Effects of aging on mRNA profiles for drug-metabolizing enzymes and transporters in livers of male and female mice. Drug Metab Dispos (2012).

Gudgeon C. J., et al. High expression of neutrophil elastase predicts improved survival in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Leuk Lymphoma (2012).

Halladay J. S., et al. An 'all-inclusive' 96-well cytochrome P450 induction method: Measuring enzyme activity, mRNA levels, protein levels, and cytotoxicity from one well using cryopreserved human hepatocytes. J Pharmacol Toxicol Methods 66(3):270-5 (2012).

Hardwick R. N., et al. Altered UDP-Glucuronosyltransferase (UGT) and Sulfotransferase (SULT) Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease. Drug Metab Dispos (2012).

Hicks S. D., et al. Evaluation of cell proliferation, apoptosis, and dna-repair genes as potential biomarkers for ethanol-induced cns alterations. BMC Neurosci 13(1):128 (2012).

Lee J. Y., et al. Immunostimulatory effect of laminarin on RAW 264.7 mouse macrophages. Molecules 17(5):5404-11 (2012).

Liang Y. J., et al. Gene profile of chemokines on hepatic stellate cells of schistosome-infected mice and antifibrotic roles of CXCL9/10 on liver non-parenchymal cells. PLoS ONE 7(8):e42490 (2012).

Lilja H., et al. An adipoinductive role of inflammation in adipose tissue engineering: key factors in the early development of engineered soft tissues. Stem Cells Dev (2012).

Mimche P. N., et al. Curcumin enhances non-opsonic phagocytosis of Plasmodium falciparum through up-regulation of CD36 surface expression on monocytes/macrophages. J Antimicrob Chemother (2012).

Preuss S. B., et al. Expression of the Arabidopsis thaliana BBX32 gene in soybean increases grain yield. PLoS ONE 7(2):e30717 (2012).

Qian X., et al. Inhibition of WISE Preserves Renal Allograft Function. J Am Soc Nephrol (2012).

Reisman S. A., et al. Bardoxolone methyl decreases megalin and activates nrf2 in the kidney. J AM Soc Nephrol (2012).

Reisman S. A., et al. Cddo-9,11-dihydro-trifluoroethyl amide (cddo-dhtfea) induces hepatic cytoprotective genes and increases bile flow in rats. Xenobiotica (2012).

Rockwell C. E., et al. Th2 Skewing by Activation of Nrf2 in CD4+ T Cells. J Immunol 188(4):1630-7 (2012).

Shuid N. A., et al. Eurycoma longifolia upregulates osteoprotegerin gene expression in androgen- deficient osteoporosis rat model. BMC Complement Altern Med 12(1):152 (2012).

Siah A., et al. Expression of RAS-like family members, c-jun and c-myc mRNA levels in neoplastic hemocytes of soft-shell clams Mya arenaria using microsphere-based 8-plex branched DNA assay. Results in Immunology 2:83-7 (2012).

Staten N. R., et al. Multiplex transcriptional analysis of paraffin-embedded liver needle biopsy from patients with liver fibrosis. Fibrogenesis Tissue Repair 5(1):21 (2012).

Tai Y. T., et al. Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma. Blood 120(9):1877-87 (2012).

Tannheimer S. L, Wright C. D. and Salmon M. Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts. Respir Res 13(1):28 (2012).

van Kessel J. C., et al. The master regulators AphA and LuxR control the Vibrio harveyi quorum-sensing regulon: analysis of their individual and combined effects. J Bacteriol (2012).

Zhao H., et al. Transcript Levels of Androgen Receptor Variant AR-V1 or AR-V7 Do Not Predict Recurrence in Patients with Prostate Cancer at Indeterminate Risk for Progression. J Urol 188(6):2158-64 (2012).


Ching L. K., et al. Transcriptional profiling of TLR-4/7/8-stimulated guinea pig splenocytes and whole blood by bDNA assay. J Immunol Methods (2011).

Csanaky I. L., et al. Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice. Hepatology 53(1):272-81 (2011).

Gan J., et al. In vitro assessment of cytochrome P450 inhibition and induction potential of tanespimycin and its major metabolite, 17-amino-17-demethoxygeldanamycin. Cancer Chemother Pharmacol (2011).

Grade M., et al. A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. Int J Cancer 128(5):1069-79 (2011).

Hall J.S., et al. Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples. Br J Cancer 104(6):971-81 (2011).

Huang L., et al. Copy number variation at 6q13 functions as a long-range regulator and is associated with pancreatic cancer risk. Carcinogenesis (2011).

Jakubikova J., et al. Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications. Blood(2011).

Jason L., et al. Increased HDAC in association with decreased plasma cortisol in older adults with chronic fatigue syndrome. Brain Behav Immun (2011).

Kamat N., et al. Characterization of vascular injury responses to stent insertion in an ex-vivo arterial perfusion model. J Vasc Interv Radiol 22(2):193-202 (2011).

Lee J. Y., Park W., Yi D. K. Immunostimulatory effects of gold nanorod and silica-coated gold nanorod on RAW 264.7 mouse macrophages. Toxicol Lett (2011).

Liles J. T., et al. Age exacerbates chronic catecholamine-induced impairments in contractile reserve in the rat. Am J Physiol Regul Integr Comp Physiol (2011).

Meng Y., et al. [Production of connective tissue growth factor by angiotensinII in human embryonic lung fibroblast via RhoA-ROCK pathway]. Zhonghua Yi Xue Za Zhi 91(16):1125-29 (2011).

More V. R., et al. Alteration of hepatic but not renal transporter expression in diet-induced obese mice. Drug Metab Dispos (2011).

Nguyen D. H., et al. Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type. Cancer Cell 19(5):640-51 (2011).

Rajashekhar G., et al. Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice. Am J Physiol Renal Physiol (2011).

Ren J., et al. Natural killer-22 cells in the synovial fluid of patients with rheumatoid arthritis are an innate source of interleukin 22 and tumor necrosis factor-α. J Rheumatol (2011).

Rutherford S. T., et al. AphA and LuxR/HapR reciprocally control quorum sensing in vibrios. Genes Dev 25(4):397-408 (2011).

Sheehy A., et al. Vascular response to coronary artery stenting in mature and juvenile swine. Cardiovasc Revasc Med (2011).

Shi Y., et al. The deubiquitinase USP2A regulates the stability of aurora-A. J Biol Chem (2011).

Shi Y., et al. Ubiquitin-specific cysteine protease 2a (USP2a) regulates the stability of Aurora-A. J Biol Chem 286(45):38960-8 (2011).

Sun Y., et al. Gene expression analysis of leprosy by using a multiplex branched DNA assay. Exp Dermatol 20(6):520-2 (2011).

Woodson S. E., et al. Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus. Virology 412(1):188-95 (2011).

Wruck C. J., et al. Extended report: role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice. Ann Rheum Dis 70(5):844-50 (2011).

Wruck C. J., et al. Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter. J Biol Chem 286(6):4493-9 (2011).

Xie J., et al. Ultrasound molecular imaging of angiogenesis induced by mutant forms of hypoxia inducible factor-1 alpha. Cardiovasc Res (2011).

Yu M., et al. Understanding the intracellular effect of enhanced nutrient feeding toward high titer antibody production process. Biotechnol Bioeng 108(5):1078-88 (2011).


Achoui M., et al. In vitro and in vivo anti-inflammatory activity of 17-O-acetylacuminolide through the inhibition of cytokines, NF-kappaB translocation and IKKbeta activity. PLoS One 5(12):e15105 (2010).

Aeby P., et al. Identifying and characterizing chemical skin sensitizers without animal testing: Colipa's research and method development program. Tocicol In Vitro 24(6):1465-73 (2010).

Aleksunes L. M., et al. Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity. J Pharmacol Exp Ther 335(1):2-12 (2010).

Aleksunes L. M., et al. Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice. J Pharmacol Exp Ther 333(1):140-51 (2010).

Cha W., et al. Development of microsphere-based multiplex branched DNA assay for detection and differentiation of avian influenza virus strains. J Clin Microbiol 48(7):2575-7 (2010).

Dhillon N. K., et al. Effect of cocaine on human immunodeficiency virus-mediated pulmonary endothelial and smooth muscle dysfunction. Am J Respir Cell Mol Biol (2010).

Jason L. A., et al. Possible genetic dysregulation in pediatric CFS. Psychology 1:247-51 (2010).

Lash G. E., et al. Multiplex cytokine analysis technologies. Expert Rev Vaccines 9(10):1231-7 (2010).

Lu H., et al. Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha. Toxicol Sci 118(2):380-90 (2010).

Lu Z., et al. [Association of HLA-DR4, PAD4, and STAT4 expression in the peripheral blood with disease activity in patients with rheumatoid arthritis]. Nan Fang Yi Ke Da Xue Xue Bao 30(6):1349-53 (2010).

Momose H., et al. A new method for the evaluation of vaccine safety based on comprehensive gene expression analysis. J Biomed Biotechnol 2010:361841 (2010).

Muid S., et al. Changes in protein and gene expression of adhesion molecules and cytokines of endothelial cells immediately following short-term spaceflight travel. Gravitational and Space Biology 23(2) (2010).

Newhall K. J., et al. Evidence for endotoxin contamination in plastic Na+-heparin blood collection tube lots. Clin Chem 56(9):1483-91 (2010).

Quinn L. S., et al. Serum and muscle interleukin-15 levels decrease in aging mice: correlation with declines in soluble interleukin-15 receptor alpha expression. Exp Gerontol 45(2):106-12 (2010).

Raymond F., et al. Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue. BMC Genomics 11(1):125 (2010).

Talluri S., et al. A G1 checkpoint mediated by the retinoblastoma protein that is dispensable in terminal differentiation but essential for senescence. Mol Cell Biol 30(4):948-60 (2010).

Tatarkiewicz K., et al. Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents. Am J Physiol Endocrinol Metab 299(6):E1076-86 (2010).

Tu K. C., et al. Negative feedback loops involving small regulatory RNAs precisely control the Vibrio harveyi quorum-sensing response. Mol Cell 37(4):567-79 (2010).

Wruck C. J., et al. Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice. Ann Rheum Dis :ard.2010.132720 (2010).

Yuk S. S., et al. Antiinflammatory effects of Epimedium brevicornum water extract on lipopolysaccharide-activated RAW264.7 macrophages. Phytother Res 24(12):1781-7 (2010).

Zhang Y. K., et al. Energy restriction does not compensate for the reduced expression of hepatic drug-processing genes in mice with aging. Drug Metab Dispos 38(7):1122-31 (2010).