Affymetrix | Panomics Solutions
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Cancer Research: Applications

Panomics assays have been proven successful under a variety of cancer research applications. Listed below are some of the case studies where Panomics assays were utilized in clinical cancer conditions.

Her2 expression in breast cancer

Visualization and quantitation of Her2 RNA transcripts in FFPE and fresh frozen tissue samples

"Excellent specificity and without interference from formalin fixation, RNA degradation, or H&E staining was obtained using both assays." Show More

Gene expression in archived FFPE prostate cancer tissues

Prostate biomarker validation in archived 9 to 13 year old H&E stained FFPE Tissues

"The author concluded that the QuantiGene Assay was well suited for clinical analysis of FFPE tissues with diagnostic or prognostic gene expression biomarker panels (Knudsen, et al., Journal of Molecular Diagnostics 10(2):169-76 (2008))." Show More

Visualize_lncRNA_in_FNA_tissue_biopsies

Detection of non-coding RNA biomarkers in fine-needle aspirate biopsies using the ViewRNA assay

"The ViewRNA ISH Tissue Assay was successfully used to analyze satellite transcripts in fine needle aspirates (FNAs) biopsies of pancreatic ductal adenocarcinomas (PDACs) in pancreatic tumor versus normal adjacent tissue." Show More

Normal_skin_Human_ARPC2

Validation of human melanoma biomarkers in FFPE samples for prognostic and predicative value

"QuantiGene Plex 2.0 Assay works directly from human melanoma and skin tissue homogenates providing a fast convenient workflow with precise and accurate simultaneous measurements of mRNAs..."Show More

TMPRSS2-ERG_fusion_gene_prostate_cancer

Detection of TMPRSS2-ERG fusion gene expression in prostate cancer specimens

"In an evaluation of clinical prostatectomy specimens, the QuantiGene 2.0 Assay detected 8 known TMPRSS2-ERG gene fusion subtypes from less than 200 pg of prostate cancer RNA."
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DNA_copy_number_analysis_CNV_CNA

Multiplex DNA copy number analysis

"With the QuantiGene Plex DNA Assay, you can quantify single-copy differences in DNA copy number and multiplex up to 34 genes per well." Show More



Breast_cancer_classification

Classification of breast cancer using the QuantiGene Plex Assay

"The data demonstrate strong correlation of the cell lines into basal or luminal subtypes and thus can be utilized to predict response to new drugs for these subtypes of breast cancer."Show More